The EPA Conventional Reduced Risk Pesticide Program

Organophosphate Pesticide Exposure Reduced Serum Paraoxonase1 (PON1) Activity Which Correlated With Oxidative Stress in Pesticide Factory Workers

Background & Aims of the Study: Serum paraoxonase (PON1) is a potent antioxidant that is associated with the pathogenesis of several diseases. Also, it is reported that environmental factors can modulate the PON1 activity. In this study, the association between the Organophosphates (OP) exposure and plasma Paraoxonase/Arylesterase (PON1) activity and also OP-induced oxidative stress was investi...

Mystery in a Bottle: Will the EPA Require Public Disclosure of Inert Pesticide Ingredients?

Risk assessment at the EPA: an agency self-exam.

Review of Pesticide Urinary Biomarker Measurements from Selected US EPA Children’s Observational Exposure Studies

Children are exposed to a wide variety of pesticides originating from both outdoor and indoor sources. Several studies were conducted or funded by the EPA over the past decade to investigate children's exposure to organophosphate and pyrethroid pesticides and the factors that impact their exposures. Urinary metabolite concentration measurements from these studies are consolidated here to identi...

EPA Regulation of Plant-Pesticides and Bt Plant-Pesticide Resistance Management

The US Environmental Protection Agency (EPA) regulates pesticides under two major statutory authorities: the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and the Federal Food Drug and Cosmetic Act (FFDCA). Under FIFRA, the EPA has the authority to regulate the development, sale, distribution, use, storage, and disposal of pesticides. To be registered, FIFRA required that a pesti...